Kelsey Grammer is pulling back the curtain on a lifelong battle with grief, addiction, and guilt in his new memoir Karen: A Brother Remembers, which confronts the brutal 1975 murder of his younger sister Karen. The Frasier actor, now 70, reveals that Karen's horrific death — she was raped and fatally stabbed just weeks before her 19th birthday — shattered his world and fueled a years-long descent into drug and alcohol abuse.
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